Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 16/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421222 | 0.89 | APP (0.41) | PGK1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8421650 | 0.86 | TLR7 (0.46) | KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8421607 | 0.85 | TLR7 (0.46) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8425349 | 0.83 | NQO1 (0.46) | PGK1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8421657 | 0.80 | FLT3 (0.50) | — | |
| SCHEMBL8423745 | 0.79 | SOD1 (0.47) | PGK1KDM4E | |
| SCHEMBL8421661 | 0.78 | SOS1 (0.38) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL8425292 | 0.77 | SOS1 (0.45) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL29919905 | 0.77 | NQO1 (0.67) | KDM4EALDH1A1HPGDHSD17B10NQO1 | |
| SCHEMBL8393507 | 0.77 | NQO1 (0.67) | KDM4EALDH1A1HPGDHSD17B10NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440787-B1 | COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR INVESTIGACION (ES) | 1999-10-13 | — | — | EP | disclosed |
| US-5719282-A | PARASITICIDES; ANTICANCER AGENTS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1998-02-17 | — | — | US | disclosed |
| EP-0440787-A1 | NEW COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1991-08-14 | — | — | EP | disclosed |