Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421485 | 0.85 | SOD1 (0.51) | SOD1MEN1KMT2AUTS2RAPP | |
| SCHEMBL8421424 | 0.82 | SOD1 (0.56) | SOD1UTS2RBCHEKDM4EELANE | |
| Hydrochloric Acid SCHEMBL8421903 | 0.80 | SOD1 (0.55) | SOD1UTS2RBCHEKDM4EELANE | |
| SCHEMBL8421243 | 0.79 | MCL1 (0.43) | SOD1BTKCYP1A2PGK1KDM4E | |
| SCHEMBL8425445 | 0.79 | PGK1 (0.47) | PGK1KDM4E | |
| SCHEMBL9207410 | 0.78 | KAT2B (0.50) | SOD1 | |
| SCHEMBL8423668 | 0.77 | SOD1 (0.49) | SOD1CYP1A2KDM4E | |
| SCHEMBL9204316 | 0.77 | TOP2A (0.52) | SOD1MEN1KMT2A | |
| SCHEMBL8600443 | 0.76 | KDM4E (0.61) | SOD1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL9205730 | 0.75 | MEN1 (0.46) | SOD1MEN1KMT2AKDM4EADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440787-B1 | COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR INVESTIGACION (ES) | 1999-10-13 | — | — | EP | disclosed |
| US-5719282-A | PARASITICIDES; ANTICANCER AGENTS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1998-02-17 | — | — | US | disclosed |
| EP-0440787-A1 | NEW COMPOUNDS OF 1,4-BIS(AMINO)BENZO(G)PHTHALAZENE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1991-08-14 | — | — | EP | disclosed |