Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310678 | 0.79 | FFAR1 (0.46) | GHSRALDH1A1TSHRLMNAMAPT | |
| SCHEMBL4310672 | 0.79 | FFAR1 (0.46) | GHSRALDH1A1TSHRLMNAMAPT | |
| SCHEMBL8425464 | 0.72 | S1PR5 (0.44) | S1PR5ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL4324159 | 0.72 | LTA4H (0.58) | ALOX5APALDH1A1FFAR1LTA4H | |
| SCHEMBL990496 | 0.72 | LTA4H (0.58) | ALOX5APALDH1A1FFAR1LTA4H | |
| SCHEMBL4319104 | 0.72 | LTA4H (0.58) | ALOX5APALDH1A1FFAR1LTA4H | |
| SCHEMBL5180568 | 0.72 | KDM1A (0.48) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL24047701 | 0.72 | HSD17B10 (0.50) | HSD17B10ALDH1A1 | |
| SCHEMBL1439128 | 0.72 | HSD17B10 (0.50) | HSD17B10ALDH1A1 | |
| SCHEMBL26430589 | 0.72 | HSD17B10 (0.50) | HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |