Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423721 | 0.89 | ALDH1A1 (0.39) | S1PR5HPGDALDH1A1CTSKFFAR4 | |
| SCHEMBL8424025 | 0.89 | ALDH1A1 (0.42) | S1PR5HPGDALDH1A1LMNACTSK | |
| SCHEMBL8424066 | 0.88 | HPGD (0.43) | S1PR5HPGDDRD4ALDH1A1PTGDR2 | |
| SCHEMBL8423588 | 0.86 | ALDH1A1 (0.43) | HPGDALDH1A1LMNAMEN1TSHR | |
| SCHEMBL8424170 | 0.75 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL8425468 | 0.72 | S1PR5 (0.40) | S1PR5ALDH1A1LMNAFFAR1MEN1 | |
| SCHEMBL8425539 | 0.71 | FKBP1A (0.42) | S1PR5HPGDALDH1A1RAB9AFKBP1A | |
| SCHEMBL6993318 | 0.70 | S1PR5 (0.41) | S1PR5HPGDALDH1A1PTGDR2TDP1 | |
| SCHEMBL8425302 | 0.69 | MMP2 (0.50) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8426091 | 0.68 | MMP2 (0.47) | L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |