Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.56 |
| ▸ | GRM5 | P41594 | 5/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.56 |
| ▸ | GRM6 | O15303 | 3/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.56 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.56 |
| ▸ | ARG1 | P05089 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425584 | 1.00 | GRM2 (0.56) | GRM2GRM5GRM1GRM6GRM4 | |
| SCHEMBL9457660 | 0.86 | GRM5 (0.40) | GRM2GRM5GRM1GRM6GRM4 | |
| SCHEMBL4692276 | 0.72 | GRM2 (1.00) | GRM2GRM5GRM1GRM6GRM4 | |
| SCHEMBL25660648 | 0.70 | GRM1 (0.62) | GRM2GRM5GRM1GRM6GRM4 | |
| SCHEMBL670022 | 0.70 | GRM1 (0.62) | GRM2GRM5GRM1GRM6GRM4 | |
| SCHEMBL10577620 | 0.70 | GRM1 (0.62) | GRM2GRM5GRM1GRM6GRM4 | |
| SCHEMBL22268519 | 0.69 | ALDH1A1 (0.42) | ALDH1A1GAAMAPT | |
| SCHEMBL1101525 | 0.69 | GRM2 (0.50) | GRM2GRM5GRM1GRM6GRM4 | |
| SCHEMBL25662353 | 0.67 | GRM2 (0.50) | GRM2GRM5GRM1GRM6GRM4 | |
| SCHEMBL2562686 | 0.67 | GRM2 (0.50) | GRM2GRM5GRM1GRM6GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872104-A | BACTERICIDES AND RESISTANT BACTERIA WITH METHYLATION INHIBITORS | ORIDIGM CORPORATION (US) | 1999-02-16 | — | — | US | disclosed |
| WO-1996020010-A1 | COMBINATION FOR REDUCING ANTIMICROBIAL RESISTANCE USING A METHYLATION INHIBITOR IN COMBINATION WITH AN ANTIBIOTIC | ORIDIGM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |