Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424096 | 0.90 | MAPT (0.43) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6948078 | 0.88 | KAT8 (0.43) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6948075 | 0.88 | KAT8 (0.43) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8425597 | 0.84 | KAT8 (0.40) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8425593 | 0.84 | KAT8 (0.40) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6949462 | 0.83 | KAT8 (0.60) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL8008959 | 0.83 | KAT8 (0.60) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL6946831 | 0.82 | KAT8 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6949450 | 0.82 | KAT8 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6951498 | 0.81 | L3MBTL1 (0.54) | MEN1KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |