Fluorene

Fluorene

SCHEMBL8425672

O=C1C=CC=C2C1=Cc1ccccc12.O=C1C=CC=C2C1=Cc1ccccc12.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.42
SRD5A2 P31213 1/20 0.36
CES1 P23141 3/20 0.36
BCHE P06276 2/20 0.36
GPR84 Q9NQS5 1/20 0.35
DRD2 P14416 2/20 0.35
DRD4 P21917 2/20 0.35
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP2 O95551 1/20 0.33
CASP3 P42574 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL851593 1.00 MAOA (0.42) MAOASRD5A2CES1BCHEGPR84
SCHEMBL49498 0.89 PTPRC (0.39) MAOACES1BCHEALDH1A1KDM4E
Bromide SCHEMBL28112337 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
SCHEMBL28084319 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL27769335 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Methane SCHEMBL29033872 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
SCHEMBL678826 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL27759355 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Benzene SCHEMBL5334270 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Fluoride SCHEMBL27765937 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5902907-A VAPOR PHASE CATALYTIC OXIDATION OF FLUORENE WITH OXYGEN-CONTAINING GAS IN PRESENCE OF CATALYST CONTAINING METAL ELEMENT OF GROUP 5 OR 6, HAVING MOLAR RATIO OF FLUORENE TO OXYGEN WITHIN SPECIFIED RANGE NIPPON SHOKUBAI CO., LTD. (JP) 1999-05-11 US disclosed