Fluorene

Fluorene

SCHEMBL851593

O=C1C=CC=C2C1=Cc1ccccc12.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.42
SRD5A2 P31213 1/20 0.36
CES1 P23141 3/20 0.36
BCHE P06276 2/20 0.36
GPR84 Q9NQS5 1/20 0.35
DRD2 P14416 2/20 0.35
DRD4 P21917 2/20 0.35
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP2 O95551 1/20 0.33
CASP3 P42574 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL8425672 1.00 MAOA (0.42) MAOASRD5A2CES1BCHEGPR84
SCHEMBL49498 0.89 PTPRC (0.39) MAOACES1BCHEALDH1A1KDM4E
Bromide SCHEMBL28112337 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
SCHEMBL28084319 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL27769335 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Methane SCHEMBL29033872 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
SCHEMBL678826 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL27759355 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Benzene SCHEMBL5334270 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E
Fluoride SCHEMBL27765937 0.87 PTPN1 (0.38) MAOACES1BCHEALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109704912-B Method for separating fluorene and fluorenone through cooling crystallization and particle size classification 天津大学 2021-05-25 CN disclosed
CN-110002986-A A kind of method of molecular oxygen oxidation synthesis fluorenes ketone compounds in water phase 郑州大学 2019-07-12 CN disclosed
CN-103804162-B Method for preparing high-purity 9-fluorenone from high-purity fluorene 宝舜科技股份有限公司 2017-04-26 CN disclosed
CN-102731281-B Method for preparing coarse fluorene and fluorenone by taking wash oil as raw material UNIV LANZHOU 2015-02-18 CN disclosed
US-8946682-B2 Donor-acceptor fluorene scaffolds: a process and uses thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-02-03 US disclosed
EP-2433323-A1 ELECTRONICALLY CONDUCTIVE POLYMER BINDER FOR LITHIUM-ION BATTERY ELECTRODE The Regents of the University of California (US) 2012-03-28 EP disclosed
US-20110210315-A1 NOVEL DONOR-ACCEPTOR FLUORENE SCAFFOLDS: A PROCESS AND USES THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-09-01 US disclosed
EP-2276733-A2 NOVEL DONOR-ACCEPTOR FLUORENE SCAFFOLDS: A PROCESS AND USES THEREOF Council Of Scientific & Industrial Research (IN) 2011-01-26 EP disclosed
WO-2010135248-A1 ELECTRONICALLY CONDUCTIVE POLYMER BINDER FOR LITHIUM-ION BATTERY ELECTRODE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-11-25 WO disclosed
WO-2009122445-A2 NOVEL DONOR-ACCEPTOR FLUORENE SCAFFOLDS : A PROCESS AND USES THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2009-10-08 WO disclosed
CN-1217908-C Method of purifying aromatic dicrrboxylic acids EASTMAN CHEM CO (US) 2005-09-07 CN disclosed
EP-1091922-A4 METHOD OF PURIFYING AROMATIC DICARBOXYLIC ACIDS EASTMAN CHEM CO (US) 2005-03-02 EP disclosed
CN-1308600-A Method for Purifying Aromatic Dicarboxylic Acids EASTMAN CHEM CO (US) 2001-08-15 CN disclosed
EP-1091922-A1 METHOD OF PURIFYING AROMATIC DICARBOXYLIC ACIDS EASTMAN CHEMICAL COMPANY (US) 2001-04-18 EP disclosed
WO-2000000457-A1 METHOD OF PURIFYING AROMATIC DICARBOXYLIC ACIDS EASTMAN CHEMICAL COMPANY (US) 2000-01-06 WO disclosed
EP-0912481-A4 1999-05-19 EP disclosed
EP-0912481-A1 PROCESS FOR MAKING FLUORENONES THE DOW CHEMICAL COMPANY (US) 1999-05-06 EP disclosed
WO-1997045393-A1 PROCESS FOR MAKING FLUORENONES THE DOW CHEMICAL COMPANY (US) 1997-12-04 WO disclosed
WO-1980000313-A1 IMPROVEMENTS IN THE STABILISATION OF HYGROSCOPIC SALTS NAT RES DEV (GB) 1980-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110210315-A1 NOVEL DONOR-ACCEPTOR FLUORENE SCAFFOLDS: A PROCESS AND USES THEREOF OCIAD1, OCIAD2, TEC MAOA 1125/4885SRD5A2 100/4885CES1 1785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.