SCHEMBL8425708

SCHEMBL8425708

Cc1ccc(C(C)Oc2ccccc2C(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.49
HSD17B10 Q99714 6/20 0.49
HPGD P15428 6/20 0.49
ALDH1A1 P00352 5/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
TSHR P16473 1/20 0.47
GGT1 P19440 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
BLM P54132 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
AKR1C3 P42330 1/20 0.46
IRAK4 Q9NWZ3 1/20 0.45
HTT P42858 1/20 0.45
LTB4R Q15722 1/20 0.44
LTB4R2 Q9NPC1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312798 0.90 KDM4E (0.54) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL10408836 0.89 KDM4E (0.53) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL10594198 0.88 KDM4E (0.49) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL8428217 0.88 ALDH1A1 (0.51) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL5710470 0.88 KDM4E (0.49) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL8424612 0.86 KMT2A (0.50) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL8428203 0.84 POLB (0.47) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL10591294 0.83 LTB4R (0.54) KDM4EHPGDALDH1A1LTB4RLTB4R2
SCHEMBL8373824 0.81 LTB4R (0.44) HSD17B10ALDH1A1TDP1LTB4RLTB4R2
SCHEMBL11428226 0.80 KDM4E (0.42) KDM4EHSD17B10HPGDALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547629-B2 Color developers and sheets thereof SANYO CHEMICAL IND LTD (JP) 1999-10-27 EP disclosed
US-5382560-A Metal salt of styrene-salicyclic acid compound SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-01-17 US disclosed
EP-0547629-A1 Color developers and sheets thereof SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1993-06-23 EP disclosed