Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425859 | 1.00 | TOP2A (0.43) | TOP2ATK1 | |
| SCHEMBL9548900 | 0.91 | TOP2A (0.42) | TOP2ATK1 | |
| SCHEMBL9548898 | 0.91 | TOP2A (0.42) | TOP2ATK1 | |
| SCHEMBL9548691 | 0.86 | TK1 (0.46) | TOP2ATK1 | |
| SCHEMBL12942600 | 0.86 | TK1 (0.46) | TOP2ATK1 | |
| SCHEMBL9548826 | 0.86 | TK1 (0.47) | TOP2ATK1 | |
| SCHEMBL9548821 | 0.86 | TK1 (0.47) | TOP2ATK1 | |
| SCHEMBL9548698 | 0.86 | TK1 (0.46) | TOP2ATK1 | |
| SCHEMBL9548641 | 0.84 | DUT (0.42) | TOP2A | |
| SCHEMBL9548646 | 0.84 | DUT (0.42) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892024-A | Bifunctional nucleosides, oligomers thereof, and methods of making and using the same | SANOFI (FR) | 1999-04-06 | — | — | US | disclosed |
| US-5677439-A | PREVENTION GENE EXPRESSION | SANOFI (FR) | 1997-10-14 | — | — | US | disclosed |
| EP-0541722-B1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING WINTHROP INC (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0541722-A1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION. | STERLING WINTHROP INC (US) | 1993-05-19 | — | — | EP | disclosed |
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |
| WO-1992002534-A2 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING DRUG, INC. (US) | 1992-02-20 | — | — | WO | disclosed |