Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 5/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CCNH | P51946 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422362 | 0.89 | SMN1; SMN2 (0.72) | GAASMN1; SMN2MCL1GUSBIDH1 | |
| SCHEMBL10576829 | 0.85 | SMN1; SMN2 (0.54) | GAASMN1; SMN2IDH1MEN1KMT2A | |
| SCHEMBL27523257 | 0.82 | GUSB (0.48) | GAASMN1; SMN2MCL1GUSBIDH1 | |
| SCHEMBL8425835 | 0.80 | MEN1 (0.56) | GAASMN1; SMN2GUSBMEN1KMT2A | |
| SCHEMBL12127309 | 0.79 | ALDH1A1 (0.60) | KMT2ALMNAMAPT | |
| SCHEMBL15658306 | 0.78 | GUSB (0.56) | GAASMN1; SMN2GUSBMEN1KMT2A | |
| SCHEMBL7015594 | 0.78 | GUSB (0.66) | GAASMN1; SMN2MCL1GUSBMEN1 | |
| SCHEMBL15661006 | 0.78 | ALDH1A1 (0.61) | GAASMN1; SMN2GUSBMEN1KMT2A | |
| SCHEMBL7580547 | 0.77 | IDH1 (0.71) | SMN1; SMN2MCL1IDH1NHERF1CDK1 | |
| SCHEMBL29041041 | 0.77 | ALB (0.57) | GAASMN1; SMN2GUSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |