Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259390 | 0.86 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL7015594 | 0.85 | GUSB (0.66) | MEN1KMT2AGUSBSMN1; SMN2MAPT | |
| SCHEMBL15660019 | 0.85 | GUSB (0.56) | MEN1KMT2AGUSBSMN1; SMN2MAPT | |
| SCHEMBL28270327 | 0.85 | GUSB (0.56) | MEN1KMT2AGUSBSMN1; SMN2MAPT | |
| SCHEMBL2240841 | 0.84 | ALPL (0.69) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL8269554 | 0.84 | GUSB (0.53) | MEN1KMT2AGUSBSMN1; SMN2MAPT | |
| SCHEMBL8422362 | 0.83 | SMN1; SMN2 (0.72) | MEN1KMT2AGUSBSMN1; SMN2MAPT | |
| SCHEMBL2243550 | 0.82 | CA2 (0.68) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL25754681 | 0.81 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL27523224 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AGUSBSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |