Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428098 | 1.00 | CTSL (0.51) | CTSLCTSBEGFR | |
| SCHEMBL8428406 | 0.88 | CTSL (0.51) | CTSLCTSB | |
| SCHEMBL8428408 | 0.88 | CTSL (0.51) | CTSLCTSB | |
| SCHEMBL8426264 | 0.88 | CTSL (0.66) | CTSLCTSB | |
| SCHEMBL8426262 | 0.88 | CTSL (0.66) | CTSLCTSB | |
| SCHEMBL8426079 | 0.87 | CTSL (0.55) | CTSLCTSBEGFR | |
| SCHEMBL8426077 | 0.87 | CTSL (0.55) | CTSLCTSBEGFR | |
| SCHEMBL8428302 | 0.83 | CTSL (0.55) | CTSLEGFR | |
| SCHEMBL8428303 | 0.83 | CTSL (0.55) | CTSLEGFR | |
| SCHEMBL27647321 | 0.78 | CTSL (0.69) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008362-A | TREATING ATHEROSCLEROSIS IN MAMMALS | WYETH | 1999-12-28 | — | — | US | claimed |
| US-6008362-A | TREATING ATHEROSCLEROSIS IN MAMMALS | WYETH | 1999-12-28 | — | — | US | disclosed |
| WO-1998057928-A1 | ELEVATION OF HDL CHOLESTEROL BY 2-(4-CHLORO -1-ARYL-BUTYLIDENE) -HYDRAZINECARBOTHIOAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |