Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425287 | 0.98 | MAOA (0.47) | MAOAMAOBMAPTALOX12LMNA | |
| SCHEMBL8428052 | 0.83 | PARP14 (0.43) | MAOALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8423914 | 0.83 | SLC6A2 (0.47) | LTA4HTSHRKDM1A | |
| SCHEMBL576211 | 0.82 | MAOA (0.57) | MAOAMAOBMAPTALOX12LMNA | |
| SCHEMBL15270965 | 0.82 | MAOA (0.57) | MAOAMAOBMAPTALOX12LMNA | |
| SCHEMBL576029 | 0.80 | MAOA (0.53) | MAOAMAOBMAPTALOX12LMNA | |
| SCHEMBL13844911 | 0.79 | MAOA (0.55) | MAOAMAOBMAPTALOX12ALDH1A1 | |
| SCHEMBL16727308 | 0.79 | MAOA (0.55) | MAOAMAOBMAPTALOX12LMNA | |
| SCHEMBL1496767 | 0.79 | MMP2 (0.43) | MAPTALOX12LMNAHTTSMN1; SMN2 | |
| SCHEMBL23295277 | 0.78 | MAOA (0.65) | MAOAMAOBMAPTALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |