Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882462 | 1.00 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL84263 | 1.00 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL5708166 | 0.95 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL5708171 | 0.95 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL19690361 | 0.95 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL29924255 | 0.95 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL29924607 | 0.95 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL231011 | 0.95 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL29405696 | 0.95 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL231012 | 0.95 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10036124-B2 | Separated treatment of paper substrate with multivalent metal salts and OBAs | INTERNATIONAL PAPER COMPANY (US) | 2018-07-31 | — | — | US | claimed |
| US-20170037578-A1 | SEPARATED TREATMENT OF PAPER SUBSTRATE WITH MULTIVALENT METAL SALTS AND OBAs | INTERNATIONAL PAPER COMPANY (US) | 2017-02-09 | — | — | US | claimed |
| US-8652593-B2 | Printable substrates with improved brightness from OBAs in presence of multivalent metal salts | INTERNATIONAL PAPER COMPANY (US) | 2014-02-18 | — | — | US | claimed |
| WO-2013112511-A2 | SEPARATED TREATMENT OF PAPER SUBSTRATE WITH MULTIVALENT METAL SALTS AND OBAS | INTERNATIONAL PAPER COMPANY (US) | 2013-08-01 | — | — | WO | claimed |
| US-20130189457-A1 | SEPARATED TREATMENT OF PAPER SUBSTRATE WITH MULTIVALENT METAL SALTS AND OBAs | INTERNATIONAL PAPER COMPANY (US) | 2013-07-25 | — | — | US | claimed |
| US-8445082-B2 | — | — | 2013-05-21 | — | — | US | claimed |
| WO-2011084396-A1 | PRINTABLE SUBSTRATES WITH IMPROVED BRIGHTNESS FROM OBAS IN PRESENCE OF MULTIVALENT METAL SALTS | INTERNATIONAL PAPER COMPANY (US) | 2011-07-14 | — | — | WO | claimed |
| US-20110151149-A1 | Printable Substrates with Improved Brightness from OBAs in Presence of Multivalent Metal Salts | INTERNATIONAL PAPER COMPANY (US) | 2011-06-23 | — | — | US | claimed |
| US-20080135805-A1 | Fluorescent Pigments for Coating Compositions | CIBA SPECIALTY CHEMICALS CORP. | 2008-06-12 | — | — | US | claimed |
| US-20070264293-A1 | Encapsulated Fluorescent Whitening Compositions and Their Use in Personal Care Applications | CIBA SPECIALTY CHEMICALS CORP. | 2007-11-15 | — | — | US | claimed |
| EP-0682145-B1 | Textile treatment | CIBA SC HOLDING AG (CH) | 2004-08-25 | — | — | EP | claimed |
| US-20020124980-A1 | Inhibition of pulp and paper yellowing using nitroxides, hydroxylamines and other coadditives | SELTZER RAYMOND R (US) | 2002-09-12 | — | — | US | claimed |
| US-6447644-B1 | PULP OR PAPER THAT STILL CONTAINS LIGNIN, AND A STERICALLY HINDERED AMINE, FOR EXAMPLE DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-10 | — | — | US | claimed |
| US-6254724-B1 | STABILIZING AMOUNT OF A HINDERED AMINE COMPOUND SELECTED DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL OR WHICH ARE THEIR HYDROXYLAMINE SALTS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-03 | — | — | US | claimed |
| US-5902454-A | Method of whitening lignin-containing paper pulps | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-05-11 | — | — | US | claimed |
| EP-0899373-A1 | Method of whitening lignin-containing pulp during manufacture | Ciba SC Holding AG (CH) | 1999-03-03 | — | — | EP | claimed |
| US-5810889-A | WITH SUNSCREEN AGENTS, EMULSIFIERS AND FABRIC FINISHING MATERIALS, FOR PROTECTIVE CLOTHING | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-22 | — | — | US | claimed |
| US-5800862-A | SUN PROTECTION FACTOR, FLUORESCENT WHITENING AGENT | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-01 | — | — | US | claimed |
| EP-0697481-A2 | Aqueous textile treatment compositions containing an ultra-violet absorbing agent | CIBA-GEIGY AG (CH) | 1996-02-21 | — | — | EP | claimed |
| EP-0682145-A2 | Textile treatment | CIBA-GEIGY AG (CH) | 1995-11-15 | — | — | EP | claimed |