SCHEMBL231012

SCHEMBL231012

C(=Cc1ccc(-c2nc3ccccc3o2)cc1)c1ccc(-c2nc3ccccc3o2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.67
RAB9A P51151 4/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
ATM Q13315 1/20 0.67
ALDH1A1 P00352 3/20 0.61
HSD17B10 Q99714 3/20 0.61
KDM4E B2RXH2 2/20 0.61
HPGD P15428 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
TP53 P04637 1/20 0.61
BCHE P06276 1/20 0.59
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
MMP8 P22894 1/20 0.58
MMP13 P45452 1/20 0.58
MAPT P10636 1/20 0.54
PTPN2 P17706 1/20 0.53
PTPN1 P18031 1/20 0.53
PTPN5 P54829 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29924607 1.00 NPC1 (0.67) NPC1RAB9AMEN1KMT2AATM
SCHEMBL231011 1.00 NPC1 (0.67) NPC1RAB9AMEN1KMT2AATM
SCHEMBL29405696 1.00 NPC1 (0.67) NPC1RAB9AMEN1KMT2AATM
SCHEMBL19690361 1.00 NPC1 (0.67) NPC1RAB9AMEN1KMT2AATM
SCHEMBL29924255 1.00 NPC1 (0.67) NPC1RAB9AMEN1KMT2AATM
SCHEMBL5708166 0.97 NPC1 (0.63) NPC1RAB9AMEN1KMT2AATM
SCHEMBL5708171 0.97 NPC1 (0.63) NPC1RAB9AMEN1KMT2AATM
SCHEMBL84263 0.95 NPC1 (0.61) NPC1RAB9AMEN1KMT2AATM
SCHEMBL84264 0.95 NPC1 (0.61) NPC1RAB9AMEN1KMT2AATM
SCHEMBL29882462 0.95 NPC1 (0.61) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250297109-A1 PHOTOINITIATOR PACKAGE COMPRISING PHOSPHINE OXIDE PHOTOINITIATORS, OXAZOLE-BASED SENSITIZERS AND AMINE ADDITIVES IGM GROUP B.V. (NL) 2025-09-25 US claimed
EP-4519377-A1 PHOTOINITIATOR PACKAGE COMPRISING PHOSPHINE OXIDE PHOTOINITIATORS, OXAZOLE-BASED SENSITIZERS AND AMINE ADDITIVES IGM Group B.V. (NL) 2025-03-12 EP claimed
WO-2025032368-A1 WHITE, HEAT SHRINK FILM AND A PROCESS OF ITS MANUFACTURING GARWARE HI-TECH FILMS LIMITED (IN) 2025-02-13 WO claimed
US-20250052927-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-13 US claimed
WO-2025032504-A2 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2025-02-13 WO claimed
US-20250034123-A1 A SYNTHESIS METHOD OF BENZOXAZOLE BASED OPTICAL BRIGHTENERS AKDENIZ CHEMSON KIMYA SANAYI VE TICARET ANONIM SIRKETI (TR) 2025-01-30 US claimed
EP-4457291-A1 A SYNTHESIS METHOD OF BENZOXAZOLE BASED OPTICAL BRIGHTENERS Akdeniz Chemson Kimya Sanayi Ve Ticaret Anonim Sirketi (TR) 2024-11-06 EP claimed
US-20240190775-A1 PRECERAMIC 3D-PRINTING MONOMER AND POLYMER FORMULATIONS HRL LABORATORIES, LLC 2024-06-13 US claimed
US-20240124364-A1 PRECERAMIC 3D-PRINTING MONOMER AND POLYMER FORMULATIONS HRL LABORATORIES, LLC 2024-04-18 US claimed
US-11891341-B2 Preceramic 3D-printing monomer and polymer formulations HRL LABORATORIES, LLC (US) 2024-02-06 US claimed
EP-0684946-B1 PROCESS FOR THE PREPARATION OF BIS(2-BENZOXAZOLYL)STILBENES EASTMAN CHEM CO (US) 1997-04-23 EP claimed
EP-0684946-A1 PROCESS FOR THE PREPARATION OF BIS(2-BENZOXAZOLYL)STILBENES. EASTMAN CHEM CO (US) 1995-12-06 EP claimed
US-5409974-A A visible outer overcoatings comprising a white pigment, a brightener mixtures of a thiophene benzoxazole and 2,2'-(1,2-ethenediyldi-4,1-phenylene)bisbenzoxazole; enhance whiteness, weatherproofing LISCO, INC. (US) 1995-04-25 US claimed
WO-1994019333-A1 PROCESS FOR THE PREPARATION OF BIS(2-BENZOXAZOLYL)STILBENES EASTMAN CHEMICAL COMPANY (US) 1994-09-01 WO claimed
US-5332828-A Process for the preparation of bis (2-benzoxazolyl) stilbenes EASTMAN KODAK COMPANY (US) 1994-07-26 US claimed
US-4745142-A POLYETHER, POLYESTER COPOLYMERS MODIFIED BY ALCOHOLS TEIJIN LIMITED (JP) 1988-05-17 US claimed
US-4679795-A Optical brighteners in golf ball covers SPALDING & EVENFLO COMPANIES, INC. (US) 1987-07-14 US claimed
EP-0220576-A1 Stainproof polyester fiber TEIJIN LIMITED (JP) 1987-05-06 EP claimed
EP-0006271-B2 WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER THE PROCTER & GAMBLE COMPANY (US) 1986-01-22 EP claimed
EP-0006271-B1 WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER THE PROCTER & GAMBLE COMPANY (US) 1982-03-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034123-A1 A SYNTHESIS METHOD OF BENZOXAZOLE BASED OPTICAL BRIGHTENERS TBXAS1, TBXA2R, XDH NPC1 4752/4885RAB9A 4880/4885MEN1 4815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.