Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426400 | 1.00 | TRPA1 (0.50) | TRPA1G6PC1NPC1RAB9AFAAH | |
| SCHEMBL7592948 | 0.93 | TRPA1 (0.50) | TRPA1G6PC1NPC1RAB9AALDH1A1 | |
| SCHEMBL7592950 | 0.93 | TRPA1 (0.50) | TRPA1G6PC1NPC1RAB9AALDH1A1 | |
| SCHEMBL5273425 | 0.85 | CYP1A2 (0.52) | G6PC1NPC1RAB9AALDH1A1GAA | |
| SCHEMBL5273422 | 0.85 | CYP1A2 (0.52) | G6PC1NPC1RAB9AALDH1A1GAA | |
| SCHEMBL11347523 | 0.84 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTPOLBALOX12 | |
| SCHEMBL3149789 | 0.84 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTPOLBALOX12 | |
| SCHEMBL14860293 | 0.84 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTPOLBALOX12 | |
| SCHEMBL2464450 | 0.84 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTPOLBALOX12 | |
| SCHEMBL2464447 | 0.84 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTPOLBALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939561-A | Process for the preparation of β-phenylisoserine and β-lactam and their analogues | RHONE-POULENCE RORER S.A. (FR) | 1999-08-17 | — | — | US | disclosed |