Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | FNTA | P49354 | 4/20 | 0.59 |
| ▸ | FNTB | P49356 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | Q9HBH1 | 2/20 | 0.50 | |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430522 | 0.92 | MAPT (0.63) | BCHEMEN1KMT2AMAPTFNTA | |
| SCHEMBL8426332 | 0.90 | FNTA (0.61) | BCHEMEN1KMT2AMAPTFNTA | |
| SCHEMBL8426652 | 0.86 | BCHE (0.67) | BCHEMEN1KMT2AMAPTLMNA | |
| SCHEMBL8426650 | 0.82 | FNTA (0.61) | BCHEMEN1KMT2AMAPTFNTA | |
| SCHEMBL8428563 | 0.78 | BCHE (0.65) | BCHEMEN1KMT2AMAPTLMNA | |
| SCHEMBL21081925 | 0.77 | POLB (0.62) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL8435143 | 0.77 | FNTA (0.66) | MEN1KMT2AMAPTFNTAFNTB | |
| SCHEMBL31302974 | 0.76 | KDM1A (0.73) | MAPTLMNAGFERNPSR1KDM1A | |
| SCHEMBL30628542 | 0.76 | KDM1A (0.73) | MAPTLMNAGFERNPSR1KDM1A | |
| SCHEMBL11441982 | 0.76 | MEN1 (0.68) | MEN1KMT2AMAPTFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861394-A | COMPOUNDS AS ANTIISCHEMIC AGENTS, TREATMENT OF STROKES, ANTIHEMORRHEGENIC AGENTS, ANTIDEPRESSANTS OR TREATMENT OF SICKKLE CELL ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | claimed |
| US-5861394-A | COMPOUNDS AS ANTIISCHEMIC AGENTS, TREATMENT OF STROKES, ANTIHEMORRHEGENIC AGENTS, ANTIDEPRESSANTS OR TREATMENT OF SICKKLE CELL ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |
| EP-0777481-A1 | USE OF N-SUBSTITUTED PHENOTHIAZINES | BAYER AG (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005837-A1 | USE OF N-SUBSTITUTED PHENOTHIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-29 | — | — | WO | disclosed |