Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428563 | 0.92 | BCHE (0.65) | BCHENPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL8426449 | 0.86 | BCHE (0.64) | BCHENPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL8428762 | 0.85 | MAPT (0.63) | BCHENPSR1MAPTLMNAKDM4E | |
| SCHEMBL15775131 | 0.78 | PPARG (0.71) | BCHENPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL8426332 | 0.78 | FNTA (0.61) | BCHENPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL8430522 | 0.78 | MAPT (0.63) | BCHENPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL3240026 | 0.76 | MAPT (0.58) | BCHEMAPTLMNAALDH1A1KDM4E | |
| SCHEMBL1262841 | 0.74 | ASAH1 (0.68) | NPSR1MAPTLMNAALDH1A1HPGD | |
| SCHEMBL1262992 | 0.74 | ASAH1 (0.68) | NPSR1MAPTLMNAALDH1A1HPGD | |
| SCHEMBL1263084 | 0.74 | ASAH1 (0.68) | NPSR1MAPTLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861394-A | COMPOUNDS AS ANTIISCHEMIC AGENTS, TREATMENT OF STROKES, ANTIHEMORRHEGENIC AGENTS, ANTIDEPRESSANTS OR TREATMENT OF SICKKLE CELL ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | claimed |