Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.48 |
| ▸ | TOP2A | P11388 | 4/20 | 0.44 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426561 | 1.00 | TK1 (0.48) | TK1TOP2ARNASE1 | |
| SCHEMBL8904501 | 0.91 | TK1 (0.47) | TK1TOP2ARNASE1 | |
| SCHEMBL8904506 | 0.91 | TK1 (0.47) | TK1TOP2ARNASE1 | |
| SCHEMBL23270835 | 0.86 | TOP2A (0.51) | TK1TOP2ARNASE1 | |
| SCHEMBL24059076 | 0.86 | TOP2A (0.51) | TK1TOP2ARNASE1 | |
| SCHEMBL12942602 | 0.86 | TOP2A (0.51) | TK1TOP2ARNASE1 | |
| SCHEMBL25752267 | 0.84 | TK1 (0.44) | TK1TOP2ARNASE1 | |
| SCHEMBL24059155 | 0.83 | TK1 (0.45) | TK1TOP2ARNASE1 | |
| SCHEMBL8904787 | 0.83 | TK1 (0.62) | TK1 | |
| SCHEMBL8904780 | 0.83 | TK1 (0.62) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892024-A | Bifunctional nucleosides, oligomers thereof, and methods of making and using the same | SANOFI (FR) | 1999-04-06 | — | — | US | disclosed |
| US-5677439-A | PREVENTION GENE EXPRESSION | SANOFI (FR) | 1997-10-14 | — | — | US | disclosed |
| EP-0701564-A1 | BIFUNCTIONAL NUCLEOSIDES, OLIGOMERS THEREOF, AND METHODS OF MAKING AND USING THE SAME | SANOFI (FR) | 1996-03-20 | — | — | EP | disclosed |
| EP-0541722-B1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING WINTHROP INC (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994022888-A1 | BIFUNCTIONAL NUCLEOSIDES, OLIGOMERS THEREOF, AND METHODS OF MAKING AND USING THE SAME | STERLINGWINTHROP INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| WO-1992002534-A2 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING DRUG, INC. (US) | 1992-02-20 | — | — | WO | disclosed |