Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | RRM1 | P23921 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427082 | 1.00 | GPR84 (0.50) | GPR84FFAR1ZDHHC7GNAI3GNAO1 | |
| SCHEMBL8425252 | 1.00 | GPR84 (0.50) | GPR84FFAR1ZDHHC7GNAI3GNAO1 | |
| SCHEMBL15006759 | 0.88 | GPR84 (0.59) | GPR84FFAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL15006890 | 0.88 | GPR84 (0.59) | GPR84FFAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL15007744 | 0.88 | GPR84 (0.59) | GPR84FFAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL30112932 | 0.88 | GPR84 (0.59) | GPR84FFAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL393686 | 0.88 | GPR84 (0.59) | GPR84FFAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL25334168 | 0.86 | GNAI3 (0.58) | GPR84FFAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL15006879 | 0.86 | GNAI3 (0.58) | GPR84FFAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL15006955 | 0.86 | GNAI3 (0.58) | GPR84FFAR1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683705-A | Sulfur-based amides and bis-amides useful against skin disorders | ESTEE LAUDER, INC. (US) | 1997-11-04 | — | — | US | claimed |
| US-5948418-A | MERCAPTANS | ESTEE LAUDER, INC. (US) | 1999-09-07 | — | — | US | disclosed |
| US-5683705-A | Sulfur-based amides and bis-amides useful against skin disorders | ESTEE LAUDER, INC. (US) | 1997-11-04 | — | — | US | disclosed |