Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.64 |
| ▸ | PGR | P06401 | 12/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.64 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423021 | 0.84 | PGR (0.62) | ARPGRNR3C2SHBGNR3C1 | |
| Mibolerone SCHEMBL565277 | 0.82 | AR (0.67) | ARPGRNR3C2SHBGNR3C1 | |
| Mibolerone SCHEMBL14275154 | 0.82 | AR (0.67) | ARPGRNR3C2SHBGNR3C1 | |
| Mibolerone SCHEMBL10603681 | 0.82 | AR (0.67) | ARPGRNR3C2SHBGNR3C1 | |
| Mibolerone SCHEMBL4362587 | 0.82 | AR (0.67) | ARPGRNR3C2SHBGNR3C1 | |
| SCHEMBL13062434 | 0.80 | AR (0.66) | ARPGRNR3C2SHBG | |
| SCHEMBL24476600 | 0.80 | AR (0.64) | ARPGRNR3C2SHBGNR3C1 | |
| SCHEMBL24476273 | 0.79 | AR (0.61) | ARPGRNR3C2SHBGNR3C1 | |
| SCHEMBL24476182 | 0.79 | AR (0.63) | ARPGRNR3C2SHBGNR3C1 | |
| SCHEMBL13013543 | 0.78 | AR (1.00) | ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582338-B1 | 17-Spiromethylene steroids | AKZO NOBEL NV (NL) | 1999-10-20 | — | — | EP | disclosed |
| US-5854235-A | 17-spiromethylene steroids | AKZO NOBEL N.V. (NL) | 1998-12-29 | — | — | US | disclosed |
| US-5712264-A | 17-spiromethylene steroids | AKZO NOBEL N.V. (NL) | 1998-01-27 | — | — | US | disclosed |
| EP-0582338-A2 | 17-Spiromethylene steroids | Akzo Nobel N.V. (NL) | 1994-02-09 | — | — | EP | disclosed |