Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.61 |
| ▸ | XDH | P47989 | 2/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 10/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605191 | 0.92 | CYP1B1 (0.72) | CYP1B1XDHPPARGCYP1A1CYP1A2 | |
| SCHEMBL8429540 | 0.90 | EGFR (0.59) | CYP1B1PPARGCYP1A2ALDH1A1POLB | |
| SCHEMBL10474033 | 0.87 | CYP1B1 (0.78) | CYP1B1XDHPPARGCYP1A1CYP1A2 | |
| SCHEMBL8429084 | 0.87 | CYP1B1 (0.59) | CYP1B1XDHPPARGCYP1A1CYP1A2 | |
| SCHEMBL2904346 | 0.87 | XDH (0.72) | CYP1B1XDHPPARGMAPTEGFR | |
| SCHEMBL7609527 | 0.86 | KDM4E (0.53) | CYP1B1CYP1A2MEN1ALDH1A1POLB | |
| SCHEMBL8427265 | 0.85 | KDM4E (0.59) | CYP1B1XDHPPARGCYP1A1CYP1A2 | |
| SCHEMBL7310271 | 0.85 | EGFR (0.57) | CYP1B1EGFR | |
| SCHEMBL8305042 | 0.84 | CYP1B1 (0.58) | CYP1B1XDHCYP1A1CYP1A2ABCC1 | |
| Recoflavone SCHEMBL29406117 | 0.84 | ABCB1 (0.59) | CYP1B1XDHPPARGCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | claimed |
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | claimed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | claimed |
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |