Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10472448 | 0.94 | CYP1A2 (0.63) | EGFRCYP1B1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL4393314 | 0.94 | CYP1B1 (0.67) | EGFRCYP1B1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8427205 | 0.90 | CYP1B1 (0.61) | EGFRCYP1B1ALDH1A1CYP1A2POLB | |
| SCHEMBL8429583 | 0.90 | CYP1B1 (0.67) | EGFRCYP1B1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL10473384 | 0.89 | CYP1B1 (0.72) | CYP1B1KDM4EALDH1A1CYP1A2POLB | |
| SCHEMBL8429585 | 0.89 | CYP1B1 (0.56) | EGFRCYP1B1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8431160 | 0.88 | ALDH1A1 (0.56) | EGFRCYP1B1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8427276 | 0.87 | CYP1B1 (0.56) | EGFRCYP1B1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8427187 | 0.87 | KDM4E (0.74) | EGFRCYP1B1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL4397722 | 0.86 | KDM4E (0.70) | CYP1B1KDM4EALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |