Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464929 | 0.79 | NOS1 (0.38) | FBP1KDM4EALDH1A1 | |
| SCHEMBL2532418 | 0.79 | CYP19A1 (0.32) | CYP2A6KDM4EALDH1A1 | |
| SCHEMBL1824256 | 0.67 | NFKB1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL10445638 | 0.66 | PDE10A (0.32) | — | |
| Hydrochloric Acid SCHEMBL28704502 | 0.65 | NFKB1 (0.32) | — | |
| SCHEMBL541185 | 0.64 | NOS1 (0.32) | FBP1KDM4EALDH1A1 | |
| SCHEMBL4729301 | 0.63 | — | — | |
| SCHEMBL31010110 | 0.62 | EGLN3 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL4296374 | 0.60 | — | — | |
| SCHEMBL6534044 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955464-A | USE OF THE RECEPTOR TYROSINE KINASE INHIBITORY PROPERTIES OF THE COMPOUNDS IN THE TREATMENT OF PROLIFERATIVE DISEASE SUCH AS CANCER | ZENECA LIMITED (GB) | 1999-09-21 | — | — | US | claimed |
| CN-1134223-A | Method for controling needless plant | DOWELANCO (US) | 1996-10-30 | — | — | CN | disclosed |