SCHEMBL8428245

SCHEMBL8428245

CCCCC(CC)COC(=O)OOOC(C)(C)C(C)C

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.49
TSHR P16473 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
ATM Q13315 1/20 0.49
ALDH1A1 P00352 6/20 0.44
CA2 P00918 5/20 0.44
RECQL P46063 1/20 0.42
LMNA P02545 3/20 0.40
MAPK1 P28482 3/20 0.40
HSD17B10 Q99714 1/20 0.40
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP14 P50281 1/20 0.38
CA1 P00915 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28772 0.87 CYP3A4 (0.53) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL9242600 0.86 TSHR (0.53) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL137584 0.85 CYP3A4 (0.50) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL93541 0.84 CYP3A4 (0.62) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL30457249 0.84 CYP3A4 (0.49) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL8428242 0.84 CYP3A4 (0.49) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL19348249 0.83 CYP3A4 (0.51) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL29157890 0.83 CYP3A4 (0.46) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL22799161 0.83 CYP3A4 (0.48) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL21900161 0.82 CYP3A4 (0.47) CYP3A4TSHRTDP1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11060786-A None JP disclosed
CN-115362182-A Hydrophilic oil-repellent polymers 住友化学株式会社 2022-11-18 CN disclosed
JP-H1160786-A PRODUCTION OF FOAMABLE STYRENIC RESIN GRANULE NOF CORP 1999-03-05 JP disclosed