Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430715 | 0.85 | IKBKB (0.32) | — | |
| SCHEMBL8430781 | 0.83 | IKBKB (0.33) | — | |
| SCHEMBL8428611 | 0.82 | — | — | |
| SCHEMBL8428371 | 0.82 | MAPT (0.39) | MAPTHPGDNPSR1LMNASMN1; SMN2 | |
| SCHEMBL8428278 | 0.68 | AMY1A (0.42) | MAPTHPGDNPSR1LMNASMN1; SMN2 | |
| SCHEMBL8428247 | 0.67 | KMT2A (0.36) | MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6505678 | 0.64 | NR1H2 (0.41) | MAPTLMNA | |
| SCHEMBL8430303 | 0.63 | MEN1 (0.40) | MAPTHPGDNPSR1LMNASMN1; SMN2 | |
| SCHEMBL9057515 | 0.61 | AR (0.50) | HPGD | |
| SCHEMBL4836695 | 0.61 | POLB (0.51) | MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965619-A | ADMINISTERING AN INDENE DERIVATIVE OF GIVEN FORMULA, SUCH AS 1-(2,4,6-TRIMETHOXYBENZYLIDENE)-5-DIMETHYLAMINO-2-METHYL-3-INDENYL ACETIC ACID, TO TREAT PRECANCEROUS LESIONS SUCH AS COLONIC ADENOMATOUS POLYPS; SIDE EFFECT REDUCTION | CELL PATHWAYS INC. (US) | 1999-10-12 | — | — | US | disclosed |