Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.59 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.43 |
| ▸ | FAP | Q12884 | 3/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061570 | 0.93 | ELANE (0.62) | ELANECTSGXIAPDPP4DPP7 | |
| SCHEMBL7408179 | 0.85 | ELANE (0.51) | ELANECTSGXIAPDPP4DPP7 | |
| SCHEMBL7408175 | 0.85 | ELANE (0.51) | ELANECTSGXIAPDPP4DPP7 | |
| SCHEMBL7335507 | 0.83 | ELANE (0.62) | ELANE | |
| SCHEMBL29641757 | 0.81 | XIAP (0.58) | ELANEXIAPDPP4DPP7FAP | |
| SCHEMBL7330373 | 0.80 | ELANE (0.61) | ELANE | |
| SCHEMBL13668934 | 0.79 | XIAP (0.48) | ELANEXIAPDPP4DPP7FAP | |
| SCHEMBL2767860 | 0.79 | XIAP (0.48) | ELANEXIAPDPP4DPP7FAP | |
| SCHEMBL14982872 | 0.79 | ELANE (0.47) | ELANEXIAPDPP4DPP7FAP | |
| Bromide SCHEMBL3164359 | 0.78 | XIAP (0.47) | ELANEXIAPDPP4DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008196-A | AN ENZYME INHIBITORS OF HUMAN NEUTROPHIL ELASTASE | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0763055-B1 | PERFLUOROALKYL KETONE INHIBITORS OF ELASTASE AND PROCESSES FOR MAKING THE SAME | MERRELL PHARMA INC (US) | 1999-11-03 | — | — | EP | disclosed |