Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428468 | 0.84 | MEN1 (0.39) | RXRAMEN1KMT2ALRRK2 | |
| SCHEMBL8430717 | 0.76 | RXRA (0.39) | RXRAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8430782 | 0.74 | RXRA (0.38) | RXRAMEN1KMT2A | |
| SCHEMBL25305589 | 0.73 | RXRA (0.46) | RXRA | |
| SCHEMBL8428613 | 0.73 | RXRA (0.37) | RXRAMEN1KMT2ALRRK2 | |
| SCHEMBL8428373 | 0.72 | RXRA (0.39) | RXRAMEN1KMT2A | |
| SCHEMBL8431725 | 0.72 | RXRA (0.36) | RXRAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8428336 | 0.72 | GCGR (0.31) | — | |
| SCHEMBL8428278 | 0.70 | AMY1A (0.42) | RXRAMEN1KMT2A | |
| SCHEMBL18245005 | 0.69 | RXRA (0.67) | RXRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965619-A | ADMINISTERING AN INDENE DERIVATIVE OF GIVEN FORMULA, SUCH AS 1-(2,4,6-TRIMETHOXYBENZYLIDENE)-5-DIMETHYLAMINO-2-METHYL-3-INDENYL ACETIC ACID, TO TREAT PRECANCEROUS LESIONS SUCH AS COLONIC ADENOMATOUS POLYPS; SIDE EFFECT REDUCTION | CELL PATHWAYS INC. (US) | 1999-10-12 | — | — | US | disclosed |