Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.53 |
| ▸ | ITGAL | P20701 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428350 | 1.00 | ITGB1 (0.53) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9782613 | 0.75 | ITGB1 (0.58) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL6968272 | 0.73 | CRBN (0.51) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL6960972 | 0.73 | CRBN (0.51) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11212045 | 0.70 | — | — | |
| SCHEMBL11032630 | 0.70 | — | — | |
| SCHEMBL7385157 | 0.70 | HDAC8 (0.47) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL7385153 | 0.70 | HDAC8 (0.47) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL26939348 | 0.69 | FFAR1 (0.50) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL11203745 | 0.69 | GLA (0.59) | ITGB1ITGA5ITGB3ITGB2ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856556-A | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0102239-B1 | AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS INTERMEDIATES IN THE PREPARATION OF CARBAPENEM ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |
| EP-0102239-A1 | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY LIMITED (JP) | 1984-03-07 | — | — | EP | disclosed |