Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8333467 | 0.99 | S1PR1 (0.38) | S1PR1CTSSCTSKKDM4EMAPT | |
| SCHEMBL8428726 | 0.83 | TP53 (0.39) | CTSSCTSKKDM4EMAPTTP53 | |
| SCHEMBL8426433 | 0.82 | POLB (0.38) | CTSSCTSKKDM4EMAPTTP53 | |
| Hydrochloric Acid SCHEMBL8337102 | 0.82 | TP53 (0.38) | CTSSCTSKKDM4EMAPTTP53 | |
| SCHEMBL7797854 | 0.81 | TMPRSS4 (0.41) | KDM4EMAPTTP53RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8332842 | 0.81 | POLB (0.38) | CTSSCTSKKDM4EMAPTTP53 | |
| Hydrochloric Acid SCHEMBL7791912 | 0.80 | TMPRSS4 (0.40) | KDM4EMAPTTP53RAB9ASMN1; SMN2 | |
| SCHEMBL8428710 | 0.80 | MAPT (0.40) | S1PR1MAPTRAB9AGAAMEN1 | |
| Hydrochloric Acid SCHEMBL8335173 | 0.79 | MAPT (0.40) | S1PR1MAPTRAB9AGAAMEN1 | |
| SCHEMBL8430503 | 0.78 | SMN1; SMN2 (0.33) | S1PR1MAPTTP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791577-B1 | Ortho-substituted benzylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicament containing them | HOECHST AG (DE) | 1999-11-03 | — | — | EP | claimed |