Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427503 | 0.89 | USP2 (0.38) | USP2SMN1; SMN2ACACBGPR119RECQL | |
| SCHEMBL4279437 | 0.81 | USP2 (0.41) | USP2SMN1; SMN2ACACBGPR119RECQL | |
| SCHEMBL4539136 | 0.79 | USP2 (0.40) | USP2SMN1; SMN2ACACBGPR119RECQL | |
| SCHEMBL15076445 | 0.78 | USP2 (0.43) | USP2SMN1; SMN2ACACBGPR119RECQL | |
| SCHEMBL31629602 | 0.78 | USP2 (0.40) | USP2SMN1; SMN2ACACBGPR119RECQL | |
| SCHEMBL21325457 | 0.77 | GPR119 (0.39) | USP2SMN1; SMN2GPR119RECQLHPGD | |
| SCHEMBL4543469 | 0.77 | USP2 (0.40) | USP2SMN1; SMN2ACACBGPR119RECQL | |
| SCHEMBL5896294 | 0.76 | USP2 (0.41) | USP2SMN1; SMN2ACACBGPR119RECQL | |
| SCHEMBL16049686 | 0.75 | USP2 (0.40) | USP2SMN1; SMN2GPR119RECQLNAMPT | |
| SCHEMBL15581870 | 0.75 | PKM (0.48) | USP2SMN1; SMN2ACACBGPR119RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973156-A | Piperidine and tetrahydropyridine derivatives | MERCK SHARP & DOME LTD. (GB) | 1999-10-26 | — | — | US | disclosed |