Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.30 |
| ▸ | CTSB | P07858 | 2/20 | 0.30 |
| ▸ | CTSS | P25774 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526117 | 0.75 | MEN1 (0.35) | ABCB1MEN1NPC1GAARAB9A | |
| SCHEMBL15641371 | 0.75 | TSHR (0.31) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL7271512 | 0.70 | MEN1 (0.39) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL10783455 | 0.67 | L3MBTL1 (0.32) | — | |
| SCHEMBL1847048 | 0.67 | PKM (0.37) | KMT2ACYP2C19HIF1AALDH1A1TSHR | |
| SCHEMBL28525378 | 0.67 | MAPK10 (0.36) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL28532959 | 0.66 | MAPK10 (0.36) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL7239167 | 0.65 | — | — | |
| SCHEMBL2763713 | 0.64 | ABCB1 (0.36) | ABCB1MEN1KMT2ACA12CA1 | |
| SCHEMBL2763715 | 0.64 | ABCB1 (0.36) | ABCB1MEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859007-A | TREATMENT OF DIABETES, OBESITY | GLAXO WELLCOME INC. (US) | 1999-01-12 | — | — | US | disclosed |