Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | BCHE | P06276 | 4/20 | 0.72 |
| ▸ | ACHE | P22303 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11171388 | 0.92 | BCHE (0.75) | MEN1KMT2ABCHEACHEALDH1A1 | |
| SCHEMBL8428979 | 0.89 | MAPK1 (0.70) | MEN1KMT2ABCHEACHEALDH1A1 | |
| SCHEMBL5239436 | 0.87 | BCHE (0.78) | MEN1KMT2ABCHEACHEALDH1A1 | |
| SCHEMBL15908348 | 0.83 | MEN1 (0.75) | MEN1KMT2ABCHEACHEALDH1A1 | |
| SCHEMBL11153456 | 0.81 | MEN1 (0.62) | MEN1KMT2ABCHEACHEALDH1A1 | |
| SCHEMBL11159776 | 0.81 | MEN1 (0.65) | MEN1KMT2ABCHEACHEALDH1A1 | |
| SCHEMBL11155513 | 0.81 | MEN1 (0.61) | MEN1KMT2ABCHEACHEALDH1A1 | |
| Chloracyzine SCHEMBL29388455 | 0.81 | ALDH1A1 (0.77) | MEN1KMT2ABCHEACHEALDH1A1 | |
| Chloracyzine SCHEMBL309939 | 0.81 | ALDH1A1 (0.77) | MEN1KMT2ABCHEACHEALDH1A1 | |
| Chloracyzine SCHEMBL30719025 | 0.81 | ALDH1A1 (0.77) | MEN1KMT2ABCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861394-A | COMPOUNDS AS ANTIISCHEMIC AGENTS, TREATMENT OF STROKES, ANTIHEMORRHEGENIC AGENTS, ANTIDEPRESSANTS OR TREATMENT OF SICKKLE CELL ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | claimed |
| US-4083976-A | SPASMOLYTIC, CORONARY-DILATANT | LIKHOSHERSTOV ARKADY MIKHAILOV | 1978-04-11 | — | — | US | disclosed |
| US-3998820-A | 4-DIAZABICYCLO-4,M,O-ALKANYL-ACYL)-PHENOTHIAZINES, THEIR ACIDIC ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR PRODUCING SAME AND USESPASMOLYTICS; CORONARY DILATANTS | LIKHOSHERSTOV ARKADY MIKHAILOV | 1976-12-21 | — | — | US | disclosed |