Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | BCHE | P06276 | 7/20 | 0.68 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.68 |
| ▸ | HRH2 | P25021 | 1/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.68 |
| ▸ | HTR2A | P28223 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618894 | 0.90 | BCHE (0.67) | MAPK1BCHEADRB3HRH2ADRA1D | |
| SCHEMBL8428842 | 0.89 | MEN1 (0.78) | MAPK1BCHEADRB3HRH2ADRA1D | |
| SCHEMBL2681239 | 0.83 | BCHE (0.70) | MAPK1BCHEADRB3HRH2ADRA1D | |
| SCHEMBL4556566 | 0.83 | MAPK1 (0.68) | MAPK1BCHEADRB3HRH2ADRA1D | |
| SCHEMBL8970221 | 0.81 | MAPK1 (0.67) | MAPK1BCHEADRB3HRH2ADRA1D | |
| SCHEMBL7982855 | 0.80 | BCHE (0.67) | MAPK1BCHEADRB3HRH2ADRA1D | |
| SCHEMBL20272375 | 0.80 | BCHE (0.71) | MAPK1BCHEADRB3HRH2ADRA1D | |
| SCHEMBL11171388 | 0.80 | BCHE (0.75) | BCHEACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL31256024 | 0.77 | NPC1 (0.71) | MAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL20272371 | 0.76 | BCHE (0.61) | MAPK1BCHEADRB3HRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861394-A | COMPOUNDS AS ANTIISCHEMIC AGENTS, TREATMENT OF STROKES, ANTIHEMORRHEGENIC AGENTS, ANTIDEPRESSANTS OR TREATMENT OF SICKKLE CELL ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | claimed |