Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427094 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MAPTGAAPKMHPGD | |
| SCHEMBL8430405 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPTGAAPKMHPGD | |
| SCHEMBL8430920 | 0.88 | ALDH1A1 (0.35) | ALDH1A1MAPTGAAPKMHPGD | |
| SCHEMBL8426833 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MAPTGAAPKMHPGD | |
| SCHEMBL10069613 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTGAAPKMHPGD | |
| SCHEMBL8428896 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL8426961 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDTHRBTP53 | |
| SCHEMBL8429057 | 0.76 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL8430913 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPTGAAPKMHPGD | |
| SCHEMBL10069625 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTNPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |