Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430405 | 0.91 | ALDH1A1 (0.41) | ALDH1A1MAPK14RAB9ANPC1POLB | |
| SCHEMBL8427094 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPK14RAB9ANPC1APP | |
| SCHEMBL10069625 | 0.88 | ALDH1A1 (0.41) | ALDH1A1MAPK14RAB9ANPC1APP | |
| SCHEMBL8430943 | 0.83 | ALDH1A1 (0.39) | ALDH1A1APPTACR1GRM5C5AR1 | |
| SCHEMBL8428900 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPK14RAB9ANPC1MAPT | |
| SCHEMBL8430882 | 0.81 | L3MBTL1 (0.41) | ALDH1A1POLBMAPT | |
| SCHEMBL10069613 | 0.80 | ALDH1A1 (0.40) | ALDH1A1RAB9ANPC1POLBMAPT | |
| SCHEMBL8426961 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPK14POLBMAPT | |
| SCHEMBL10069623 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPK14RAB9ANPC1POLB | |
| SCHEMBL10069632 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPK14RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | claimed |
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |