Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 11/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427244 | 0.93 | POLB (0.60) | KDM4EALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL8427202 | 0.90 | KDM4E (0.54) | KDM4EALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL8429592 | 0.90 | XDH (0.52) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8308046 | 0.87 | MAOB (0.52) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL8429193 | 0.86 | POLB (0.48) | KDM4EALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL8309333 | 0.84 | CYP1B1 (0.57) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL8305036 | 0.84 | MAPT (0.59) | CYP1A2CYP3A4CYP2C9CYP2C19EGFR | |
| SCHEMBL8427570 | 0.83 | HPGD (0.64) | KDM4EALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL8427185 | 0.83 | POLB (0.47) | KDM4EALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL8305322 | 0.83 | CYP1B1 (0.43) | KDM4EALDH1A1CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |