Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | CREB1 | P16220 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308046 | 0.89 | MAOB (0.52) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL8429592 | 0.89 | XDH (0.52) | MAPTABCB1BCL2BCL2L1EGFR | |
| SCHEMBL8309333 | 0.86 | CYP1B1 (0.57) | MAPTNPC1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8859506 | 0.85 | CYP1B1 (0.43) | MAPTABCB1BCL2BCL2L1EGFR | |
| SCHEMBL8305652 | 0.85 | CYP1B1 (0.43) | MAPTABCB1BCL2BCL2L1EGFR | |
| SCHEMBL8305322 | 0.85 | CYP1B1 (0.43) | MAPTABCB1BCL2BCL2L1EGFR | |
| SCHEMBL8306988 | 0.84 | CYP1B1 (0.42) | MAPTABCB1BCL2BCL2L1EGFR | |
| SCHEMBL8429201 | 0.84 | KDM4E (0.51) | MAPTEGFRRETKDRCYP3A4 | |
| SCHEMBL8427185 | 0.82 | POLB (0.47) | MAPTABCB1NPC1CYP3A4CYP2C9 | |
| SCHEMBL8307482 | 0.81 | AKT1 (0.56) | MAPTKDRNPC1ABCG2CREB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |