Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530521 | 0.74 | ENPP2 (0.47) | ENPP2CFDMGLLPRMT3CARM1 | |
| SCHEMBL8430854 | 0.73 | DHODH (0.43) | ENPP2CFDMGLLHDAC1 | |
| SCHEMBL8531192 | 0.71 | PTGER4 (0.48) | ENPP2MGLLPLAUPLAT | |
| SCHEMBL8432519 | 0.69 | PTGER4 (0.45) | ENPP2MGLL | |
| SCHEMBL8532444 | 0.69 | ENPP2 (0.46) | ENPP2CFDMGLLBTKCNR1 | |
| SCHEMBL8431178 | 0.67 | PLA2G10 (0.39) | ENPP2 | |
| SCHEMBL8532339 | 0.65 | ENPP2 (0.44) | ENPP2CFDMGLLCNR1PRMT3 | |
| SCHEMBL8429182 | 0.65 | PTGER4 (0.44) | ENPP2HDAC1HDAC6 | |
| SCHEMBL8531524 | 0.65 | ENPP2 (0.39) | ENPP2BTKCNR1NR1H4L3MBTL1 | |
| SCHEMBL8432447 | 0.65 | PARP1 (0.37) | ENPP2NQO2MGLLCNR1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952381-A | SELECTIVELY INHIBITING OR ANTAGONIZING THE INTEGRINS; ANTITUMOR AGENTS, ANTIARTHRITIC AGENTS, VIRICIDES, MICROBIOCIDES; TREATING OSTEOPOROSIS, SKIN DISORDERS | G. D. SEARLE & CO. (US) | 1999-09-14 | — | — | US | disclosed |