Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027835 | 0.85 | MEN1 (0.47) | NNMTMEN1KMT2AMAPK3MAPT | |
| SCHEMBL10201866 | 0.82 | NNMT (0.47) | NNMTMEN1KMT2AMAPK3POLB | |
| SCHEMBL30340520 | 0.79 | MEN1 (0.40) | NNMTMEN1KMT2AMAPK3MAPT | |
| SCHEMBL15922260 | 0.79 | MEN1 (0.40) | NNMTMEN1KMT2AMAPK3MAPT | |
| SCHEMBL29953242 | 0.77 | MEN1 (0.41) | NNMTMEN1KMT2AMAPTGAA | |
| SCHEMBL16115971 | 0.77 | MEN1 (0.41) | NNMTMEN1KMT2AMAPTGAA | |
| SCHEMBL677094 | 0.76 | MEN1 (0.43) | NNMTMEN1KMT2AMAPTGAA | |
| SCHEMBL17071825 | 0.76 | MEN1 (0.49) | MEN1KMT2AMAPK3MAPTGAA | |
| SCHEMBL13073943 | 0.75 | UHRF1 (0.46) | SLC22A12CYP2A6GPBAR1 | |
| SCHEMBL20845927 | 0.75 | NNMT (0.41) | NNMTMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953566-A2 | Selective transformation of pyridines with electrophiles | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-03 | — | — | EP | disclosed |