Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15616200 | 0.83 | GABRP (0.40) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL16782987 | 0.82 | MAPK1 (0.38) | MAPTGAANPSR1MCOLN3ULK1 | |
| SCHEMBL21027835 | 0.79 | MEN1 (0.47) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL17808198 | 0.78 | MBOAT4 (0.35) | MEN1KMT2AMAPTNPSR1ULK1 | |
| SCHEMBL17071825 | 0.78 | MEN1 (0.49) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL15464741 | 0.77 | IL1B (0.39) | MAPTGAANPSR1MBOAT4L3MBTL1 | |
| SCHEMBL20907133 | 0.76 | MEN1 (0.42) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL19544344 | 0.76 | UHRF1 (0.40) | MEN1KMT2AMAPTNPSR1ULK1 | |
| SCHEMBL30510541 | 0.76 | UHRF1 (0.40) | MEN1KMT2AMAPTNPSR1ULK1 | |
| SCHEMBL8429223 | 0.76 | NNMT (0.46) | MEN1KMT2AMAPTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12264147-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | Propellon Therapeutics Inc. (CA) | 2025-04-01 | — | — | US | disclosed |
| EP-4466258-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| US-20240383875-A1 | Benzimidazole Pyridine Derivatives | HOFFMANN-LA ROCHE INC. (US) | 2024-11-21 | — | — | US | disclosed |
| CN-118591534-A | Novel benzimidazole pyridine derivatives | 豪夫迈·罗氏有限公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |
| US-11976057-B2 | MrgX2 antagonists | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-05-07 | — | — | US | disclosed |
| EP-4225746-A1 | MRGX2 ANTAGONISTS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2023-08-16 | — | — | EP | disclosed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |
| US-20230219926-A1 | SUBSTITUTED CARBOXAMIDES AS INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING | FACIT INC. (CA) | 2023-07-13 | — | — | US | disclosed |
| CN-101822253-A | The method of control of microbicide compositions and plant disease | ISHIHARA SANGYO KAISHA | 2010-09-08 | — | — | CN | disclosed |
| CN-100581362-C | Bactericide composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA | 2010-01-20 | — | — | CN | disclosed |
| US-20090247763-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| CN-101215260-A | Method for preparing benzoylpyridine derivatices and salt thereof | ISHIHARA SANGYO KAISHA (JP) | 2008-07-09 | — | — | CN | disclosed |
| CN-101199274-A | Bactericide composition and method for controlling plant disease | ISHIHARA SANGYO KAISHA (JP) | 2008-06-18 | — | — | CN | disclosed |
| CN-1874680-A | bactericide composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA (JP) | 2006-12-06 | — | — | CN | disclosed |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1679003-A1 | BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-20060089390-A1 | 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-04-27 | — | — | US | disclosed |
| EP-1559320-A1 | 3-BENZOYL-2,4,5-SUBSTITUTED PYRIDINE DERIVATIVES OR SALTS THEREOF AND BACTERICIDES CONTAINING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247763-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CBR1, CNPY2 | MEN1 3117/4885KMT2A 2040/4885MAPT 4140/4885 |
| US-12264147-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | WDR5, WDR82, WDR1 | MEN1 3660/4885KMT2A 355/4885MAPT 2234/4885 |
| US-20240383875-A1 | Benzimidazole Pyridine Derivatives | H1-3, H1-2, H1-4 | MEN1 1114/4885KMT2A 925/4885MAPT 2944/4885 |
| US-11976057-B2 | MrgX2 antagonists | MRGPRX2, MRGPRX1, MRGPRX4 | MEN1 455/4885KMT2A 2000/4885MAPT 2184/4885 |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | CBR3, CNPY2, PAH | MEN1 3219/4885KMT2A 2575/4885MAPT 4366/4885 |
| US-20230219926-A1 | SUBSTITUTED CARBOXAMIDES AS INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING | WDR5, WDR82, WDR1 | MEN1 3660/4885KMT2A 355/4885MAPT 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.