Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 3/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31390858 | 0.88 | CHEK2 (0.49) | PARP10TDP1L3MBTL1PARP1TYMS | |
| SCHEMBL1485298 | 0.80 | PIK3CA (0.39) | PARP10PARP1CYP19A1 | |
| SCHEMBL1484989 | 0.77 | LMNA (0.38) | PARP10PARP11 | |
| SCHEMBL598138 | 0.76 | TDP1 (0.61) | PARP10TDP1L3MBTL1PARP1TYMS | |
| SCHEMBL13740452 | 0.76 | CES1 (0.43) | PARP10PARP1PARP11HTR2C | |
| SCHEMBL12177490 | 0.72 | NPY5R (0.49) | PARP10PARP1TYMSSRD5A1 | |
| SCHEMBL6071274 | 0.71 | MAPK10 (0.41) | TDP1AURKBHTR2AHTR2C | |
| SCHEMBL20229560 | 0.70 | TYMS (0.47) | PARP10TDP1L3MBTL1PARP1TYMS | |
| SCHEMBL12177491 | 0.69 | DRD4 (0.47) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL358939 | 0.69 | TDP1 (0.81) | PARP10TDP1L3MBTL1PARP1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945382-A | AND A METHOD OF THEIR PREPARATION BY CHLORINATION OF AN INTERMEDIATE ARYLPYRAZOLE; PROTECTION AGAINST FUNGAL DISEASES IN TOMATO, RICE, AND WHEAT PLANTS | RHONE-POULENC AGROCHIMIE (FR) | 1999-08-31 | — | — | US | disclosed |