Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.64 |
| ▸ | CCR5 | P51681 | 3/20 | 0.64 |
| ▸ | CCR8 | P51685 | 3/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | GRM5 | P41594 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16352566 | 0.96 | CCR1 (0.64) | CCR1CCR5CCR8ADORA2AADORA1 | |
| SCHEMBL18697686 | 0.90 | CCR1 (0.58) | CCR1CCR5CCR8ADORA2AADORA1 | |
| SCHEMBL5108411 | 0.88 | CCR1 (0.56) | CCR1CCR5CCR8ADORA2AADORA1 | |
| SCHEMBL25463227 | 0.87 | CCR1 (0.55) | CCR1CCR5CCR8ADORA2AADORA1 | |
| SCHEMBL22081696 | 0.87 | ADORA2A (0.57) | CCR1CCR5CCR8ADORA2AADORA1 | |
| SCHEMBL16672906 | 0.84 | KDM4E (0.68) | CCR1CCR5CCR8GRM5KDM4E | |
| SCHEMBL550801 | 0.83 | GRM5 (0.62) | CCR1CCR5CCR8GRM5KDM4E | |
| SCHEMBL29726791 | 0.83 | GRM5 (0.62) | CCR1CCR5CCR8GRM5KDM4E | |
| SCHEMBL9958026 | 0.83 | CCR1 (0.70) | CCR1CCR5CCR8ADORA2AADORA1 | |
| SCHEMBL27911207 | 0.82 | KDM1A (0.51) | CCR1CCR5CCR8ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
| US-20220315556-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-10-06 | — | — | US | disclosed |
| CN-109273615-B | Organic light-emitting device | 长春海谱润斯科技有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-109273615-A | A kind of organic luminescent device | 长春海谱润斯科技有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-109251194-A | A kind of triaizine compounds and its organic luminescent device of the class formation containing fluorenes | 长春海谱润斯科技有限公司 | 2019-01-22 | — | — | CN | disclosed |
| US-5892061-A | REACTING A MONO- OR POLYCARBOXYLIC ACID WITH A MONO- OR POLYAMIDE IN THE PRESENCE OF A HALOIMINIUM SALT AND BASE; CATALYST SELECTIVITY | MITSUI CHEMICALS, INC. (JP) | 1999-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315556-A1 | FURIN INHIBITORS | FURIN, TGFB1, PCSK7 | CCR1 1031/4885CCR5 1197/4885CCR8 1753/4885 |
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | CCR1 1031/4885CCR5 1197/4885CCR8 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.