SCHEMBL550801

SCHEMBL550801

Clc1cccc(-c2ccccn2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 5/20 0.62
PKM P14618 2/20 0.62
TP53 P04637 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
NPC1 O15118 1/20 0.62
MITF O75030 1/20 0.62
MAPT P10636 1/20 0.62
TSHR P16473 1/20 0.62
RAB9A P51151 1/20 0.62
CCR1 P32246 3/20 0.55
CCR5 P51681 3/20 0.55
CCR8 P51685 3/20 0.55
CNR2 P34972 1/20 0.55
CNR1 P21554 1/20 0.54
CYP19A1 P11511 1/20 0.53
DCTPP1 Q9H773 1/20 0.52
PIM1 P11309 1/20 0.51
KDM4E B2RXH2 3/20 0.50
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29726791 1.00 GRM5 (0.62) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL26824783 0.91 GRM5 (0.57) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL31039976 0.85 GRM5 (0.56) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL29679578 0.85 KDM4E (0.62) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL502867 0.85 KDM4E (0.62) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL15683870 0.84 GRM5 (0.67) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL30340631 0.84 GRM5 (0.67) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL15684056 0.84 GRM5 (0.62) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL8429326 0.83 CCR1 (0.64) GRM5PKMTP53SMN1; SMN2NPC1
SCHEMBL16352566 0.83 CCR1 (0.64) GRM5PKMTP53SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070349-A Organic light-emitting compound and organic electroluminescent device comprising the same 索路思高新材料有限公司 2026-05-19 CN disclosed
CN-115322192-A Pyrrolo [3,4-b ] pyridine derivatives, and synthesis method and application thereof 重庆文理学院 2022-11-11 CN disclosed
CN-105992767-B WNT pathway modulators 新加坡科技研究局 2019-06-21 CN disclosed
US-9682958-B2 Ligands and their preparation MERCK PATENT GMBH (DE) 2017-06-20 US disclosed
US-9682958-B2 Ligands and their preparation MERCK PATENT GMBH (DE) 2017-06-20 US disclosed
US-9592235-B2 Aminoquinazoline and pyridopyrimidine derivatives GENENTECH, INC. (US) 2017-03-14 US disclosed
US-20160296525-A1 AMINOQUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES GENENTECH, INC. (US) 2016-10-13 US disclosed
CN-105899488-A Process for fluorinating compounds 美国陶氏益农公司 2016-08-24 CN disclosed
US-20150175574-A1 Ligands And Their Preparation MERCK PATENT GMBH (DE) 2015-06-25 US disclosed
US-20150175574-A1 Ligands And Their Preparation MERCK PATENT GMBH (DE) 2015-06-25 US disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
WO-2007129810-A1 SYNTHESIS OF VINYLPHENYLPYRIDINE AND LIVING ANIONIC POLYMERIZATION GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-11-15 WO disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
CN-1875026-A Platinum complex and luminescent element TAKASAGO PERFUMERY CO LTD (JP) 2006-12-06 CN disclosed
WO-2006127948-A2 N-TERMINALLY MODIFIED GLP-1 RECEPTOR MODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2006-11-30 WO disclosed
US-20060202197-A1 Platinum complex and light-emitting device TAKASAGO INTERNATIONAL CORPORATION 2006-09-14 US disclosed
EP-1683804-A2 PLATINUM COMPLEX AND LUMINESCENT ELEMENT Takasago International Corporation (JP) 2006-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070103060-A1 Platinum complex and light emitting device UBE2D3, PCID2, CCND2 GRM5 1971/4885PKM 3822/4885TP53 2075/4885
US-20160296525-A1 AMINOQUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES DPYD, FANCD2, RECQL GRM5 1954/4885PKM 604/4885TP53 32/4885
US-20060202197-A1 Platinum complex and light-emitting device RAD1, RAD51, UACA GRM5 2608/4885PKM 3533/4885TP53 1619/4885
US-20150175574-A1 Ligands And Their Preparation PNMT, DNMT1, DNMT3A GRM5 395/4885PKM 1916/4885TP53 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.