Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetophenone SCHEMBL28270527 | 0.89 | SMN1; SMN2 (0.60) | MAPTSMN1; SMN2HPGDALDH1A1LMNA | |
| Pyrogallol SCHEMBL9797828 | 0.84 | CA1 (0.67) | MAPTSMN1; SMN2HPGDALDH1A1LMNA | |
| Pyrogallol SCHEMBL8433563 | 0.84 | CA1 (0.67) | MAPTSMN1; SMN2HPGDALDH1A1LMNA | |
| Acetophenone SCHEMBL16745259 | 0.83 | — | — | |
| Acetophenone SCHEMBL30537000 | 0.83 | — | — | |
| Acetophenone SCHEMBL27462873 | 0.83 | MAPT (0.71) | MAPTSMN1; SMN2HPGDALDH1A1LMNA | |
| Acetophenone SCHEMBL737 | 0.83 | — | — | |
| Acetophenone SCHEMBL30537005 | 0.83 | — | — | |
| Acetophenone SCHEMBL1450855 | 0.83 | — | — | |
| Acetophenone SCHEMBL719033 | 0.83 | MAPT (0.71) | MAPTSMN1; SMN2HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965688-A | FORMING AN ALIPHATIC CHLOROFORMATE AND THEN REACTING THE BISCHLOROFORMATE WITH AROMATIC DIOL IN AN INTERFACIAL POLYMERIZATION REACTION TO FORM A COPOLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 1999-10-12 | — | — | US | claimed |
| CN-102127044-A | Method for synthesizing 5,7-dihydroxy flavone | SHAANXI JIAHE PHYTOCHEM CO LTD | 2011-07-20 | — | — | CN | disclosed |
| CN-1228445-A | Interfacial polycarbonate polymerization process and product | GEN ELECTRIC (US) | 1999-09-15 | — | — | CN | disclosed |