Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429524 | 1.00 | THRA (0.43) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL9640876 | 0.93 | RARB (0.43) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL9640884 | 0.93 | RARB (0.43) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL8774164 | 0.91 | THRA (0.44) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL8774005 | 0.91 | THRA (0.44) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL8774160 | 0.91 | THRA (0.44) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL8773991 | 0.91 | THRA (0.44) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL8774167 | 0.91 | THRA (0.44) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL8773974 | 0.91 | THRA (0.44) | THRATHRBPTPN11S1PR1S1PR3 | |
| SCHEMBL8774112 | 0.91 | THRA (0.44) | THRATHRBPTPN11S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959061-A1 | 3,3'-DIFLUOROBIPHENYL DERIVATIVES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY ELEMENTS | CHISSO CORPORATION (JP) | 1999-11-24 | — | — | EP | disclosed |