Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640884 | 1.00 | RARB (0.43) | RARBRARAPTPN11THRATHRB | |
| SCHEMBL10336087 | 0.93 | RARB (0.43) | RARBRARAPTPN11THRATHRB | |
| SCHEMBL8429522 | 0.93 | THRA (0.43) | RARBRARAPTPN11THRATHRB | |
| SCHEMBL8429524 | 0.93 | THRA (0.43) | RARBRARAPTPN11THRATHRB | |
| SCHEMBL8774062 | 0.91 | PTPN11 (0.43) | RARBRARAPTPN11THRATHRB | |
| SCHEMBL10490741 | 0.88 | RARB (0.42) | RARBRARA | |
| SCHEMBL9485570 | 0.85 | PTPN11 (0.38) | RARBPTPN11S1PR1S1PR3S1PR5 | |
| SCHEMBL9486720 | 0.85 | PTPN11 (0.38) | RARBPTPN11S1PR1S1PR3S1PR5 | |
| SCHEMBL9485575 | 0.85 | PTPN11 (0.38) | RARBPTPN11S1PR1S1PR3S1PR5 | |
| SCHEMBL9486718 | 0.85 | PTPN11 (0.38) | RARBPTPN11S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357702-B1 | FLUORINATED OLIGOPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0357702-A1 | FLUORINATED OLIGOPHENYL DERIVATIVES. | MERCK PATENT GMBH (DE) | 1990-03-14 | — | — | EP | disclosed |
| WO-1989006678-A1 | FLUORINATED OLIGOPHENYL DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-07-27 | — | — | WO | disclosed |