Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425112 | 1.00 | FFAR4 (0.39) | FFAR4FFAR1S1PR1S1PR3BACE1 | |
| SCHEMBL8425111 | 1.00 | FFAR4 (0.39) | FFAR4FFAR1S1PR1S1PR3BACE1 | |
| SCHEMBL8426672 | 0.81 | S1PR1 (0.39) | FFAR4FFAR1S1PR1S1PR3CA2 | |
| SCHEMBL8426649 | 0.80 | CA2 (0.49) | CA2 | |
| SCHEMBL8426648 | 0.80 | CA2 (0.49) | CA2 | |
| SCHEMBL8426761 | 0.80 | CA2 (0.49) | CA2 | |
| SCHEMBL8425944 | 0.78 | PNMT (0.38) | FFAR4FFAR1 | |
| SCHEMBL8424902 | 0.78 | PNMT (0.38) | FFAR4FFAR1 | |
| SCHEMBL8424903 | 0.78 | PNMT (0.38) | FFAR4FFAR1 | |
| SCHEMBL16650295 | 0.78 | CA2 (0.38) | CA2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925662-A | OXIDASE INHIBITORS | SYNTHELABO (FR) | 1999-07-20 | — | — | US | disclosed |
| EP-0859776-A1 | COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017347-A1 | COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-05-15 | — | — | WO | disclosed |