Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9591308 | 0.76 | SMAD3 (0.43) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL4022543 | 0.74 | SMAD3 (0.48) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL8977198 | 0.73 | ALDH1A1 (0.39) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL1608754 | 0.72 | SMAD3 (0.46) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL10868252 | 0.72 | ALDH1A1 (0.36) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL2186619 | 0.71 | CYP3A4 (0.40) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL10481145 | 0.71 | HPGD (0.36) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL4007803 | 0.71 | CYP3A4 (0.38) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL9308167 | 0.70 | HPGD (0.40) | SMAD3ALDH1A1RECQLTDP1HPGD | |
| SCHEMBL9244110 | 0.70 | AHR (0.44) | SMAD3ALDH1A1RECQLTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630278-B1 | NON-TOXIC, ENVIRONMENTALLY BENIGN FIRE EXTINGUISHANTS | TAG INVESTMENTS INC (CA) | 1999-11-24 | — | — | EP | disclosed |